Single-nucleotide polymorphisms in the ELANE (Elastase, Neutrophil Expressed) gene are associated with severe congenital neutropenia, while the ELANE gene provides instructions for making a protein called neutrophil elastase.We identified disease susceptibility single-nucleotide polymorphisms (SNPs) in the ELANE gene using several computational too

Prostate cancer is relatively unique to man.There is no naturally occurring prostate cancer in the mouse.Pre-clinical studies involve the establishment of a genetically engineered mouse prostate cancer model with features close to those of the human situation.A new knock-in mouse adenocarcinoma prostate (KIMAP) model was established, which showed c

Nigeria is passing through a period of uncertainty and pervasive economic recession which has further aggravated the problem of poverty and unemployment among Nigerian youths.These jobless youths take solace in all form of atrocities and social Dimensional Wall Art vices that pose a serious threat to sustainable development of the nation.This resea

Although steel reinforcements are HYDRATING CURL CREAM used to withstand tensile forces in concrete, cracks are an unavoidable phenomenon.The presence of cracks, in fact, increases the risk for lowering the service life and durability of concrete structures.A critical issue occurs when due to splitting forces, cracks appear in concrete along the te